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Invitrogen
Methylenedioxymethamphetamine Recombinant Mouse Monoclonal Antibody (3G3)
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Methylenedioxymethamphetamine Antibody (MA566416) in SDS-PAGE
SDS-PAGE characterization of Methylenedioxymethamphetamine under reducing conditions. Lane M: Protein marker (kDa); Lane MDMA: Purified Methylenedioxymethamphetamine Recombinant Monoclonal (Product # MA566416). Methylenedioxymethamphetamine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-324.
产品信息
MA566416
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3G3
抗原
Conjugate of MDMA hapten and KLH.
偶联物
形式
Liquid
浓度
5.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a synthetic amphetamine derivative that primarily affects serotonergic and dopaminergic systems. MDMA preferentially stimulates the release of serotonin (5HT) and results in relatively smaller increases in synaptic dopamine (DA), which contributes to its psychoactive effects. Structurally, MDMA is similar to hallucinogenic compounds such as mescaline and amphetamine, and it is often formulated as a racemate, a 1:1 mixture of its enantiomers. The (S)-enantiomer is metabolized faster than the (R)-enantiomer. MDMA's neurotoxicity has been a focus of research, particularly its impact on serotonin levels and its potential to induce reactive oxygen species. It is also known for its empathogenic effects, making it popular in recreational settings. MDMA's pharmacological properties have been studied extensively, including its effects on mesenchymal stem cells and dental pulp stem cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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