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Invitrogen
Midkine Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5150201
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant Midkine (MK) (Ala22-Asp143)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amphiregulin-associated protein; FLJ27379; midgestation and kidney protein; midkine (neurite growth-promoting factor 2); MK; neurite growth-promoting factor 2; neurite outgrowth-promoting factor 2; retinoic acid inducible factor
基因别名: ARAP; MK; NEGF2
UniProt ID: (Human) P21741, (Rat) Q9R1S9
Entrez Gene ID: (Human) 4192, (Pig) 100359358, (Rat) 81517
behavioral fear response
leukocyte chemotaxis involved in inflammatory response
T cell activation involved in immune response
positive regulation of leukocyte chemotaxis
cytoskeleton organization
negative regulation of cell adhesion
signal transduction
nervous system development
short-term memory
response to xenobiotic stimulus
response to wounding
response to hormone
negative regulation of cardiac muscle cell apoptotic process
positive regulation of epithelial to mesenchymal transition
positive regulation of macrophage chemotaxis
positive regulation of keratinocyte proliferation
positive regulation of neuron projection development
response to auditory stimulus
cell migration
dentate gyrus development
cerebellar granular layer development
hippocampus development
cerebral cortex development
cell differentiation
negative regulation of ossification
adrenal gland development
positive regulation of cell migration
defecation
regulation of chondrocyte differentiation
positive regulation of interleukin-12 production
intracellular signal transduction
tissue regeneration
negative regulation of neuron apoptotic process
estrous cycle
positive regulation of T cell differentiation
negative regulation of regulatory T cell differentiation
positive regulation of cell adhesion
positive regulation of transcription, DNA-templated
regulation of bone remodeling
oogenesis
positive regulation of oligodendrocyte differentiation
positive regulation of inflammatory response
regulation of behavior
response to glucocorticoid
positive regulation of cartilage development
positive regulation of smooth muscle cell chemotaxis
positive regulation of neutrophil chemotaxis
negative regulation of canonical Wnt signaling pathway
negative regulation of inflammatory response to wounding
positive regulation of inflammatory response to wounding
glial cell projection elongation
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of leukocyte cell-cell adhesion
negative regulation of epithelial cell apoptotic process
positive regulation of leukocyte adhesion to vascular endothelial cell
positive regulation of blood vessel branching
positive regulation of vascular endothelial cell proliferation
positive regulation of artery morphogenesis
positive regulation of neural precursor cell proliferation
positive regulation of hepatocyte proliferation
positive regulation of neutrophil extravasation
positive regulation of neuron migration
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