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Immunogen sequence: MEFAELIKTP RVDNVVLHRP FYPAVEGTLC LTGHHLILSS RQDNTEELWL LHSNIDAIDK RFVGSLGTII IKCKDFRIIQ LDIPGMEECL NIASSIEALS TLDSITLMYP FFYRPMFEVI EDGWHSFLPE QEFELYSSAT SEWRLSYVNK EFAVCPSYPP IVTVPKSIDD EALRKVATFR HGGRFPVLSY YHKKNGMVIM RSGQPLTGTN GRRCKEDEKL INATLRAGKR GYIIDTRSLN VAQQTRAKGG; Positive Samples: HepG2, HeLa, Jurkat, A-549, Mouse brain, Rat brain, Rat lung; Cellular Location: Cytoplasm
This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZP434K171; Inactive phosphatidylinositol 3-phosphatase 9; MGC126672; myotubularin related protein 8; Myotubularin-related protein 9
基因别名: 9430075G12Rik; AA516943; AF073881; C8orf9; LIP-STYX; mMTMH3; Mtmr3; MTMR8; MTMR9
UniProt ID: (Human) Q96QG7, (Mouse) Q9Z2D0
Entrez Gene ID: (Human) 66036, (Mouse) 210376, (Rat) 282584