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          • Primary Antibodies ›
          • MyD88 Antibodies

          Fabgennix

          MyD88 Polyclonal Antibody

          View all (28) MyD88 antibodies

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          Cite MyD88 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          MyD88 Antibody in Western Blot (WB)
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          MyD88 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MyD88 Antibody (MYD88-101AP) in WB

          WB of MYD88-101AP with PC-MYD88. 1:500 antibody dilution in DiluObuffer. Apparent MW is 58 kDa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          MyD88 Antibody in Western Blot (WB)
          MyD88 Polyclonal Antibody

          Product Details

          MYD88-101AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          1:50-1:250
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Non-human primate, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 140-190 on human MyD88 protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: mutant myeloid differentiation primary response 88; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; Myeloid differentiation primary response protein MyD88; myleoid differentiation primary response protein; TLR adaptor MYD88; unnamed protein product

          View more View less

          Gene Aliases: IMD68; MYD88; MYD88D; WM1

          View more View less

          UniProt ID: (Human) Q99836, (Rat) Q6Y1S1, (Mouse) P22366

          View more View less

          Entrez Gene ID: (Human) 4615, (Rat) 301059, (Mouse) 17874

          View more View less

          Function(s)
          receptor binding Toll binding death receptor binding cytokine receptor binding interleukin-1 receptor binding protein binding Toll-like receptor binding signaling adaptor activity identical protein binding binding, bridging TIR domain binding ATP-dependent histone chaperone activity scaffold/adaptor protein
          Process(es)
          response to molecule of fungal origin leukocyte activation involved in inflammatory response neutrophil activation involved in immune response immune system process MyD88-dependent toll-like receptor signaling pathway chromatin organization chromatin remodeling phagocytosis apoptotic process inflammatory response signal transduction cell surface receptor signaling pathway JNK cascade Toll signaling pathway response to virus induced systemic resistance gene expression regulation of gene expression positive regulation of gene expression microglia differentiation response to amine immunoglobulin mediated immune response cytokine-mediated signaling pathway neurogenesis lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production response to peptidoglycan response to lipopolysaccharide regulation of interleukin-6 production regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interleukin-1 beta production positive regulation of interleukin-17 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production toll-like receptor 4 signaling pathway regulation of toll-like receptor 4 signaling pathway toll-like receptor 5 signaling pathway toll-like receptor 8 signaling pathway NIK/NF-kappaB signaling toll-like receptor TLR6:TLR2 signaling pathway interleukin-33-mediated signaling pathway regulation of cell proliferation defense response to bacterium defense response to protozoan positive regulation of I-kappaB kinase/NF-kappaB signaling response to amino acid skin development innate immune response response to ethanol positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation regulation of inflammatory response defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity defense response to virus type I interferon signaling pathway positive regulation of macrophage cytokine production interleukin-1-mediated signaling pathway response to interleukin-1 3'-UTR-mediated mRNA stabilization neutrophil mediated killing of bacterium cellular response to lipopolysaccharide cellular response to mechanical stimulus establishment of endothelial intestinal barrier cellular response to oxidised low-density lipoprotein particle stimulus positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly regulation of neutrophil migration regulation of chemokine (C-X-C motif) ligand 1 production regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of growth of symbiont in host positive regulation of chemokine biosynthetic process type I interferon biosynthetic process immune response transmembrane receptor protein serine/threonine kinase signaling pathway
          It has to be done as per old AB suggested Products section.

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