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PA5-16672 targets Myeloperoxidase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16672 immunogen is purified human granulocytic MPO.
PA5-16672 detects MPO-DNA complexes in purified PMA-induced human neutrophil extracellular traps in ELISA application.
Concentration is not determined for this particular antibody. The final product is manufactured from stock material based upon a dilution ratio. The antibody is still quality tested to ensure expected performance and lot-to-lot consistency.
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MPO; Myeloperoxidase
基因别名: mKIAA4033; MPO
UniProt ID: (Human) P05164, (Mouse) P11247
Entrez Gene ID: (Human) 4353, (Rat) 303413, (Mouse) 17523