Invitrogen

N-WASP Monoclonal Antibody (C.427.3)

Name: N-WASP Monoclonal Antibody (C.427.3)
Brand: Invitrogen
SKU: MA5-15011

高级验证

查看其他20个N-WASP抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)
高级验证 (2)

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N-WASP Antibody (MA5-15011) in WB

Western blot was performed using N-WASP Monoclonal Antibody (C.427.3) (Product # MA5-15011) and a~60 kDa band corresponding to WASL was observed in SkBr3, SHSY5Y, A431, MCF7 Mouse Lung and Mouse Cerebellum; and was absent in HEL 92.1.7, HL60 and Mouse skeletal Muscle. Whole cell extracts (30 µg lysate) of SkBr3 (Lane 1), SHSY5Y (Lane 2), A431 (Lane 3), MCF7 (Lane 4), HEL92.1.7 (Lane 5), HL60 (Lane 6), tissue extracts (30 µg lysate) of Mouse Lung (Lane 7), Mouse Cerebellum (Lane 8) and Mouse Skeletal Muscle (Lane 9) were electrophoresed usi... View More

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产品信息

MA5-15011

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫沉淀 (IP)

1:50

产品规格

种属反应

Bovine, Hamster, Human, Mouse, Non-human primate, Rat

宿主/亚型

Rabbit / IgG

分类

Monoclonal

类型

Antibody

克隆号

C.427.3

抗原

Synthetic peptide corresponding the sequence of human N-WASP

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

8 µg/mL

纯化类型

Affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

<0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_10984648

产品详细信息

It is not recommended to aliquot this antibody.

靶标信息

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Actin nucleation-promoting factor WASL; DKFZp779G0847; MGC48327; n wasp; N-WASP; Neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like

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基因别名: 2900021I12Rik; 3110031I02Rik; N-WASP; NWASP; TRS4; WASL; WASPB

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UniProt ID: (Bovine) Q95107, (Human) O00401, (Mouse) Q91YD9