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Invitrogen
NAE1 Polyclonal Antibody
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NAE1 Antibody (PA5-95233) in WB
Western blot analysis of NAE1 using NAE1 Polyclonal Antibody (Product # PA5-95233). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel)/90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human SH-SY5Y whole cell lysates. Lane 2: human U251 whole cell lysates. Lane 3: human U20S whole cell lysates. Lane 4: rat brain tissue lysates. Lane 5: mouse brain tissue lysates. Lane 7: mouse kidney tissue lysates. After electrophoresis, proteins wer... View More
产品信息
PA5-95233
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human APPBP1 recombinant protein (Position: E181-L534).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human SH-SY5Y whole cell, human U251 whole cell, human U20S whole cell, rat brain tissue, mouse brain tissue, mouse kidney tissue lysates .|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; APP-BP1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; Proto-oncogene protein 1; protooncogene protein 1
基因别名: 59kDa; A-116A10.1; APPBP1; HPP1; NAE1; ula-1
UniProt ID: (Human) A8MU28, (Mouse) Q8VBW6
Entrez Gene ID: (Human) 8883, (Mouse) 234664, (Rat) 84019
