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Invitrogen
NAM8 Polyclonal Antibody
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NAM8 Antibody (PA5-144487) in WB
Western blot analysis of NAM8 in recombinant protein using a dilution of 1:2,000. Samples were incubated with NAM8 polyclonal antibody (Product # PA5-144487). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 28.2 kDa. Observed band size: 30 kDa.
产品信息
PA5-144487
产品规格
种属反应
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) (Baker's yeast) NAM8 protein
偶联物
形式
Liquid
浓度
3.28 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Component of the U1 small nuclear ribonucleoprotein complex (U1 snRNP) involved in the initiation of meiotic recombination (PubMed:1603056, PubMed:7625279). Involved in the formation of DSBs at recombination hot-spots through meiosis-specific splicing of REC107 pre-mRNA (PubMed:7625279, PubMed:9112441, PubMed:21788335). Collaborates with MER1 to promote splicing of essential meiotic mRNAs REC10, AMA1, MER3, HFM1, SPO22 and PCH2 (PubMed:10983980, PubMed:21208980, PubMed:21788335). NAM8 interacts with the pre-mRNA downstream of the 5' splice site, in a region of non-conserved sequence and is required for efficient splicing of uncapped RNA precursor (PubMed:10072385).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MRE2; MUD15; Nuclear accommodation of mitochondria protein 8; Protein NAM8; U1 snRNP component NAM8
基因别名: MRE2; MUD15; NAM8; YHR086W
UniProt ID: (Baker's yeast) Q00539
Entrez Gene ID: (Baker's yeast) 856486
