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Immunogen sequence: WFLAKKPWTR YVDIALRTDM SDITKSYLSE CGSCFWVGES EEKVVGTVGA LPVDDPTLRE KRLQLFHLSV DNEHRGQGIA KALVRTVLQF A; Positive Samples: Rat brain; Cellular Location: Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type II membrane protein
The protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acetyltransferase 1; ATase1; camello-like 1 like; Camello-like protein 1; camello-like protein 2; Camello-like protein 6; N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene); N-acetyltransferase Camello 2; Probable N-acetyltransferase 8B; probable N-acetyltransferase CML6
基因别名: Cml1; CML2; Cml6; Hcml2; Nat8; Nat8b; NAT8BP; RGD621605
UniProt ID: (Rat) Q9JIY6
Entrez Gene ID: (Human) 51471, (Rat) 171084