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Abnova
NCK2 Polyclonal Antibody, MaxPab™
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NCK2 Antibody (H00008440-B01P) in WB
Western Blot analysis of NCK2 expression in transfected 293T cell line (H00008440-T01) by NCK2 MaxPab polyclonal antibody.
Lane 1: NCK2 transfected lysate(41.8 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NCK2 transfected lysate(41.8 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00008440-B01P
产品规格
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NCK2 (NP_001004720.1, 1 a.a. approximately 380 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN SLKKGSLVKN LKDTLGLGKT RRKTSARDAS PTPSTDAEYP ANGSGADRIY DLNIPAFVKF AYVAEREDEL SLVKGSRVTV MEKCSDGWWR GSYNGQIGWF PSNYVLEEVD EAAAESPSFL SLRKGASLSN GQGSRVLHVV QTLYPFSSVT EEELNFEKGE TMEVIEKPEN DPEWWKCKNA RGQVGLVPKN YVVVLSDGPA LHPAHAPQIS YTGPSSSGRF AGREWYYGNV TRHQAECALN ERGVEGDFLI RDSESSPSDF SVSLKASGKN KHFKVQLVDN VYCIGQRRFH TMDELVEHYK KAPIFTSEHG EKLYLVRALQ
靶标信息
The NCK family of SH2/SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling, including the EGF and PDGF receptor-pathways, to downstream signaling proteins. The NCK2 protein binds human PDGFR-b (Tyr-1009); overexpression of NCK2 inhibits PDGF-induced membrane ruffling and lamellipod formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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