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Invitrogen
NCS1 Polyclonal Antibody
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NCS1 Antibody (PA5-92988) in WB
Western blot analysis of NCS1 in extracts of various cell lines. Samples were incubated with NCS1 Polyclonal antibody (Product # PA5-92988) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-92988
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NCS1 (NP_0551012)
偶联物
形式
Liquid
浓度
2.98 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQFFPFGD PTKFATFVFN VFDENKDGRI EFSEFIQALS VTSRGTLDEK LRWAFKLYDL DNDGYITRNE MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DGKLTLQEFQ EGSKADPSIV QALSLYDGLV; Positive Samples: HeLa, SW620, MCF-7, U-251MG, Mouse bone marrow, Rat kidney; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Golgi apparatus, Golgi stack membrane, Lipid-anchor, Membrane, Peripheral membrane protein, perinuclear region, postsynaptic cell membrane, postsynaptic density, synapse
靶标信息
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: frequenin; Frequenin homolog; Frequenin-like protein; Frequenin-like ubiquitous protein; NCS-1; Neuronal calcium sensor 1; neuronal calcium sensor-1
基因别名: 9430075O15Rik; A730032G13Rik; AI836659; FLUP; FREQ; Mfreq; NCS-1; NCS1
UniProt ID: (Human) P62166, (Mouse) Q8BNY6, (Rat) P62168
Entrez Gene ID: (Human) 23413, (Mouse) 14299, (Rat) 65153
