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Invitrogen
NDUFS4 Recombinant Mouse Monoclonal Antibody (K06372_10H6)
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NDUFS4 Antibody (MA564452) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NDUFS4 in formalin-fixed paraffin-embedded stomach tissue. Samples were incubated with NDUFS4 recombinant monoclonal (Product # MA564452) using a dilution of 6.2 µg/mL at room temperature for 1 hr followed by Poly-peroxidase conjugated goat anti-mouse IgG. Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endog... View More
产品信息
MA564452
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K06372_10H6
抗原
Recombinant human NDUFS4 (aa 51-160).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QLITVDEKLD ITTLTGVPEE HIKTRKVRIF VPARNNMQSG VNNTKKWKME FDTRERWENP LMGWASTADP LSNMVLTFST KEDAVSFAEK NGWSYDIEER KVPKPKSKSY
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%, Pig - 95%, Cynomolgus monkey - 98%.
靶标信息
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CI-18 kDa; CI-AQDQ; complex I 18kDa subunit; Complex I-18 kDa; Complex I-AQDQ; mitochondrial respiratory chain complex I (18-KD subunit); NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH-ubiquinone oxidoreductase 18 kDa subunit
基因别名: 6720411N02Rik; AQDQ; C1-18k; CI-18; CI-18 kDa; CI-AQDQ; NDUFS4
UniProt ID: (Human) O43181, (Mouse) Q9CXZ1
Entrez Gene ID: (Human) 4724, (Mouse) 17993
regulation of protein phosphorylation
mitochondrial electron transport, NADH to ubiquinone
brain development
cAMP-mediated signaling
mitochondrial respiratory chain complex I assembly
cellular respiration
positive regulation of fibroblast proliferation
response to cAMP
reactive oxygen species metabolic process
transport
electron transport chain
oxidation-reduction process
