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Invitrogen
NEIL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-62913
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
40 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KSKATQLSPE DRVEDALPPS KAPSRTRRAK RDLPKRTATQ RPEGTSLQQD PEAPTVPKKG RRKGRQAASG HCRPRKVKAD IPSLEPE
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 48%.
靶标信息
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; endonuclease VIII; endonuclease VIII-like 1; FLJ22402; NEH1; nei endonuclease VIII-like 1; nei homolog 1; nei-like protein 1; unnamed protein product
基因别名: FPG1; hFPG1; NEI1
UniProt ID: (Human) Q96FI4
Entrez Gene ID: (Human) 79661
nucleic acid binding
damaged DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
protein binding
zinc ion binding
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing N-glycosyl compounds
lyase activity
DNA N-glycosylase activity
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
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