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Invitrogen
NEK6 Recombinant Rabbit Monoclonal Antibody (24GB755)
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NEK6 Antibody (MA5-57506) in ICC/IF
Immunocytochemical staining of NEK6 in HT-1080 cells using NEK6 Recombinant Monoclonal Antibody (Product # MA5-57506) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; NEK6 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-57506
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB755
抗原
A synthesized peptide derived from human NEK6 (aa 250-313)
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related expressed kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA-related expressed kinase 6; NIMA-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID
基因别名: 1300007C09Rik; NEK6; SID6-1512
UniProt ID: (Human) Q9HC98, (Mouse) Q9ES70, (Rat) P59895
Entrez Gene ID: (Human) 10783, (Mouse) 59126, (Rat) 360161
magnesium ion binding
protein serine/threonine kinase activity
signal transducer activity
protein binding
ATP binding
kinesin binding
protein kinase binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
non-receptor serine/threonine protein kinase
cytokinesis
protein phosphorylation
apoptotic process
chromosome segregation
mitotic nuclear division
mitotic nuclear envelope disassembly
signal transduction
regulation of mitotic cell cycle
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
G2 DNA damage checkpoint
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein autophosphorylation
spindle assembly
regulation of cellular senescence
cell cycle
regulation of signal transduction
phosphorylation
cell division
