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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LDPADLTHDT TGLTAKELEA LDEVFTKVYK AKYPIVGYTA RRILNEDGSP NLDFKPEDQP
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 92%.
NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell immortalization-related protein 2; Neudesin; Neuron-derived neurotrophic factor; Protein GIG47; Secreted protein of unknown function; SPUF protein
基因别名: CIR2; NENF; SPUF
Entrez Gene ID: (Human) 29937