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Invitrogen
NET1 Polyclonal Antibody
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产品信息
PA5-18217
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (DKALSGGKRKETLV) corresponding to the C-terminus amino acids of NET1 (aa 583-596).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: guanine nucleotide regulatory protein (oncogene); Neuroepithelial cell-transforming gene 1 protein; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor (GEF) 8; Rho guanine nucleotide exchange factor 8; RP11-116G8.1; small GTP-binding protein regulator
基因别名: ARHGEF8; NET1; NET1A
UniProt ID: (Human) Q7Z628
Entrez Gene ID: (Human) 10276
regulation of cell growth
signal transduction
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
myoblast migration
cellular response to hydrogen peroxide
cellular response to ionizing radiation
positive regulation of substrate adhesion-dependent cell spreading
