Invitrogen

NF-H Monoclonal Antibody (3G3)

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NF-H Monoclonal Antibody (3G3)

产品信息

MA1-2012

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:100-1:1,000
-

免疫组化 (IHC)

-
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免疫组化（石蜡） (IHC (P))

1:10-1:100
-

免疫细胞化学 (ICC/IF)

5 µg/mL
-

免疫沉淀 (IP)

-
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产品规格

种属反应

Human, Rat

已发表种属

C. elegans, Fruit fly, Human, Mouse, Rabbit

宿主/亚型

Mouse

分类

Monoclonal

类型

Antibody

克隆号

3G3

抗原

Synthetic peptide corresponding to 226 amino acids of the C-terminus of neurofilament, heavy chain.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

purified

保存液

PBS with 1mg/mL BSA

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_347005

产品详细信息

MA1-2012 detects the neurofilament, heavy chain in human and rat samples.

MA1-2012 has been successfully used in Western blot, immunohistochemistry and immunofluorecence procedures. By Western blot this antibody detects a ~200 kDa protein representing the neurofilament, heavy chain in rat brain microsome. In immunohistochemistry procedures MA1-2012 recognizes the neurofilament, heavy chain in rat hippocampal neurons.

The MA1-2012 immunogen is a synthetic peptide corresponding to 226 amino acids of the C-terminus of neurofilament, heavy chain.

靶标信息

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: 200 kDa neurofilament protein; NEF3; neurofilament; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF 200 kD; NF-H; NHC

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基因别名: CMT2CC; KIAA0845; NEFH; NFH

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UniProt ID: (Human) P12036

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Entrez Gene ID: (Human) 4744, (Rat) 24587

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