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Recommended positive controls: HeLa.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (91%), Pig (99%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold "handshake" motif in a manner analogous to the histone proteins H2B and H2A, respectively.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CCAAT-binding transcription factor subunit A; nf-y; NF-YB; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; Transcription factor NF-Y, B subunit
基因别名: AA985999; CBF-A; CBF-B; HAP3; NF-YB; NFYB
UniProt ID: (Human) P25208, (Mouse) P63139
Entrez Gene ID: (Human) 4801, (Mouse) 18045