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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 98%, Rat- 98%.
Sequence of this protein is as follows: QEKRKTINGE DILFAMSTLG FDSYVEPLKL YLQKFREAMK GEKGIGGAVT ATDGLSEELT EEAFTNQLPA GLITTDGQQQ NVMVYTTSYQ QISGVQQIQF S
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold "handshake" motif in a manner analogous to the histone proteins H2B and H2A, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAAT box DNA-binding protein subunit B; nf-y; NF-YB; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta
基因别名: HAP3; NFYB
Entrez Gene ID: (Human) 4801