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Abnova
NFYC Polyclonal Antibody, MaxPab™
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NFYC Antibody (H00004802-D01P) in WB
Western Blot analysis of NFYC expression in transfected 293T cell line (H00004802-T01) by NFYC MaxPab polyclonal antibody.
Lane 1: NFYC transfected lysate(37.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NFYC transfected lysate(37.20 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00004802-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NFYC (NP_055038.2, 1 a.a. approximately 335 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MSTEGGFGGT SSSDAQQSLQ SFWPRVMEEI RNLTVKDFRV QELPLARIKK IMKLDEDVKM ISAEAPVLFA KAAQIFITEL TLRAWIHTED NKRRTLQRND IAMAITKFDQ FDFLIDIVPR DELKPPKRQE EVRQSVTPAE PVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQQITQT EVQQGQQQFS QFTDGQQLYQ IQQVTMPAGQ DLAQPMFIQS ANQPSDGQAP QVTGD
靶标信息
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold "handshake" motif in a manner analogous to the histone proteins, H2B and H2A, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAAT box DNA-binding protein subunit C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; DKFZp667G242; FLJ45775; histone H1 transcription factor large subunit 2A; NF-YC; Nuclear transcription factor Y subunit C; Nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; transactivator HSM-1; Transactivator HSM-1/2; transcription factor NF-Y, C subunit
基因别名: CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC; NFYC
UniProt ID: (Human) Q13952
Entrez Gene ID: (Human) 4802
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
DNA-binding transcription factor
