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Invitrogen
NFYC Polyclonal Antibody
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产品信息
PA5-106696
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NFYC(Accession Q13952), corresponding to amino acid residues A65-I115.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total NFYC.
靶标信息
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold "handshake" motif in a manner analogous to the histone proteins, H2B and H2A, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAAT box DNA-binding protein subunit C; CAAT-box DNA-binding protein subunit C; CBF-C; CCAAT binding factor of CBF-C/NFY-C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; CCAAT-binding transcription factor subunit C; DKFZp667G242; FLJ45775; histone H1 transcription factor large subunit 2A; NF-YC; Nuclear transcription factor Y subunit C; Nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; transactivator HSM-1; Transactivator HSM-1/2; transcription factor NF-Y, C subunit
基因别名: CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC; NFYC
UniProt ID: (Human) Q13952, (Mouse) P70353, (Rat) Q62725
Entrez Gene ID: (Human) 4802, (Mouse) 18046, (Rat) 25337
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
sequence-specific DNA binding
DNA-binding transcription factor
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein folding
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of transcription, DNA-templated
