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Abnova
NFYC Monoclonal Antibody (1D3)
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产品信息
H00004802-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D3
抗原
NFYC (AAH05003, 14 a.a. approximately 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: DAQQSLQSFW PRVMEEIRNL TVKDFRVQEL PLARIKKIMK LDEDVKMISA EAPVLFAKAA QIFITELTLR AWIHTEDNKR RTLQRNDIAM AITKFDQFDF
靶标信息
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold "handshake" motif in a manner analogous to the histone proteins, H2B and H2A, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAAT box DNA-binding protein subunit C; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; DKFZp667G242; FLJ45775; histone H1 transcription factor large subunit 2A; NF-YC; Nuclear transcription factor Y subunit C; Nuclear transcription factor Y subunit gamma; nuclear transcription factor Y, gamma; transactivator HSM-1; Transactivator HSM-1/2; transcription factor NF-Y, C subunit
基因别名: CBF-C; CBFC; H1TF2A; HAP5; HSM; NF-YC; NFYC
UniProt ID: (Human) Q13952
Entrez Gene ID: (Human) 4802
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
DNA-binding transcription factor
