Invitrogen

NFkB P100 Polyclonal Antibody

Name: NFkB P100 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-88086
Availability: InStock

查看其他26个NFkB p100抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (2)

NFkB P100 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 2

NFkB P100 Antibody (PA5-88086) in ICC/IF

Immunofluorescence analysis of NFkB p52 in U2OS cells. Samples were incubated with NFkB p52 Polyclonal antibody (Product # PA5-88086) using a dilution of 1:100. Blue: DAPI for nuclear staining.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image NFkB P100 Polyclonal Antibody

产品信息

PA5-88086

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-?B2 (NP_0024933)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.11 mg/mL

111 µg

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2804639

产品详细信息

Immunogen sequence: AGADIHAENE EPLCPLPSPP TSDSDSDSEG PEKDTRSSFR GHTPLDLTCS TKVKTLLLNA AQNTMEPPLT PPSPAGPGLS LGDTALQNLE QLLDGPEAQG SWAELAERLG LRSLVDTYRQ TTSPSGSLLR SYELAGGDLA GLLEALSDMG LEEGVRLLRG PETRDKLPST EVKEDSAYGS QSVEQEAEKL GPPPEPPGGL CHGHPQPQVH; Positive Samples: Jurkat, MCF7, NCI-H460, Mouse thymus; Cellular Location: Cytoplasm, Nucleus

靶标信息

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DNA-binding factor KBF2; NF kappaB2; NF-kB p100; Nuclear factor NF-kappa-B p100 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

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基因别名: lyt; NF-kappaB2; Nfkb2; p49; p49/p100; p50B; p52

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UniProt ID: (Mouse) Q9WTK5

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Entrez Gene ID: (Mouse) 18034

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功能

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding Rel homology transcription factor

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