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Invitrogen
NIBP Polyclonal Antibody
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NIBP Antibody (PA5-110514) in WB
Western blot analysis of NIBP in extracts of mouse pancreas. Samples were incubated with NIBP Polyclonal antibody (Product # PA5-110514) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-110514
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 947-1246 of human TRAPPC9 (NP_113654.4).
偶联物
形式
Liquid
浓度
1.44 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SHVKTLEAVL NFKYSGGPGH TEGYYRNLSL GLHVEVEPSV FFTRVSTLPA TSTRQCHLLL DVFNSTEHEL TVSTRSSEAL ILHAGECQRM AIQVDKFNFE SFPESPGEKG QFANPKQLEE ERREARGLEI HSKLGICWRI PSLKRSGEAS VEGLLNQLVL EHLQLAPLQW DVLVDGQPCD REAVAACQVG DPVRLEVRLT NRSPRSVGPF ALTVVPFQDH QNGVHNYDLH DTVSFVGSST FYLDAVQPSG QSACLGALLF LYTGDFFLHI RFHEDSTSKE LPPSWFCLPS VHVCALEAQA
靶标信息
NIBP is a 1246 amino acid intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its neuronal expression NIBP is considered as a potential target for modulating the NF-(kappa) B signaling cascade in neuronal pathologies dependent upon abnormal activation of this pathway. NIBP is mainly expressed in brain, muscle, heart, and kidney.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IKK2 binding protein; NIK and IKK(beta) binding protein; NIK and IKK-beta binding protein; NIK- and IKBKB-binding protein; Trafficking protein particle complex subunit 9; TRAPP 120 kDa subunit; Tularik gene 1 protein
基因别名: 1810044A24Rik; 2900005P22Rik; 4632408O18Rik; IBP; IKBKBBP; KIAA1882; mKIAA1882; MRT13; NIBP; T1; TRAPPC9; TRS120; TRS130
UniProt ID: (Human) Q96Q05, (Mouse) Q3U0M1
Entrez Gene ID: (Human) 83696, (Mouse) 76510
