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Invitrogen
NIPSNAP1 Polyclonal Antibody
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产品信息
PA5-20501
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid peptide from near the center of human NIPSNAP.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is human brain tissue lysate.
PA5-20501 can be used with blocking peptide PEP-0621.
靶标信息
NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1; NipSnap1; Protein NipSnap homolog 1
基因别名: NIPSNAP1
UniProt ID: (Human) Q9BPW8, (Mouse) O55125
Entrez Gene ID: (Human) 8508, (Rat) 360971, (Mouse) 18082
