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Invitrogen
NLGN4X Polyclonal Antibody
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产品信息
PA5-43378
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human NLGN4X
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: ELFSCNFSKN DVMLSAVVMT YWTNFAKTGD PNQPVPQDTK FIHTKPNRFE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
Neuroligin-4, X linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge together the synaptic cleft and have an essential role in synaptic transmissions between neurons. There are 5 neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). The expression of neuroligin-4, X-linked has been reported on human pluripotent stem cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HNLX; MGC22376; Neuroligin X; Neuroligin-4, X-linked; NLGN
基因别名: ASPGX2; AUTSX2; HLNX; HNL4X; KIAA1260; NLGN4; NLGN4X; UNQ365/PRO701
UniProt ID: (Human) Q8N0W4
Entrez Gene ID: (Human) 57502
brainstem development
neuron cell-cell adhesion
learning
cerebellum development
neuron differentiation
adult behavior
social behavior
organ growth
cell-cell junction organization
synapse organization
vocalization behavior
negative regulation of excitatory postsynaptic potential
presynaptic membrane assembly
