Invitrogen

NMDAR3A/NMDAR3B Monoclonal Antibody (K35/40.1)

Name: NMDAR3A\/NMDAR3B Monoclonal Antibody (K35\/40.1)
Brand: Invitrogen
SKU: MA1-10881

1 篇参考文献

查看其他2个NMDAR3A/NMDAR3B抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA1-10881

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-10 µg/mL

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

K35/40.1

抗原

Fusion protein of NR3A amino acids 780-914 from the extracellular III-IV loop.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.4 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2232559

产品详细信息

MA1-10881 detects Glutamate NMDA Receptor NR3A/B Subunit from human, mouse, and rat samples. This antibody does not cross-react with subunits NR1 or NR2A-D.

MA1-10881 has been successfully used in Western blot and immunoprecipitation applications.

The MA1-10881 immunogen is Fusion protein of NR3A amino acids 780-914 from the extracellular III-IV loop.

靶标信息

Grin3a is an NMDA (N-methyl-D-aspartate) receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Grin3a is mediated by glycine and may play a role in the development of dendritic spines. Further, Grin3a may play a role in PPP2CB-NMDAR mediated signaling mechanism. Grin3a belongs to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. Grin3a shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in Grin3a suggest that the protein may be involved in the development of synaptic elements by modulating NMDA receptor activity. Diseases associated with GRIN3A include Lingual-Facial-Buccal Dyskinesia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: GluN3A; GluN3B; glutamate [NMDA] receptor subunit 3A; glutamate [NMDA] receptor subunit 3B; glutamate receptor; Glutamate receptor chi-1; Glutamate receptor ionotropic, NMDA 3A; Glutamate receptor ionotropic, NMDA 3B; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; glutamate receptor, ionotropic, N-methyl-D-aspartate 3B; glutamate receptor, ionotropic, NMDA3B; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subtype 3A; N-methyl-D-aspartate receptor subtype 3B; N-methyl-D-aspartate receptor subunit NR3B; NMDA receptor 4; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR-L; NMDAR-L1; NMDAR3A; NMDAR3B; Nr4

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基因别名: 6430537F04; A830097C19Rik; chi-1; GluN3A; GluN3B; GRIN3A; GRIN3B; KIAA1973; mKIAA1973; NMDAR-L; NMDAR3B; NR3; NR3A; NR3B