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产品信息
H00004831-M06
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D3
抗原
NME2 (NP_002503, 51 a.a. approximately 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
靶标信息
Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2.7.13.3; C-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; expressed in non-metastatic cells 2; expressed in non-metastatic cells 2 protein; HEL-S-155an; Histidine protein kinase NDKB; NDK B; NDP kinase alpha; NDP kinase B; nm23-H2; nm23-M2; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; Nucleoside diphosphate kinase B; nucleoside-diphosphate kinase 2; nucleotide diphosphate kinase B; P18
基因别名: NDKB; NDPK-B; NDPKB; nm23-2; NM23-H2; nm23-M2; NM23B; NME2; p18-12d; PUF
UniProt ID: (Human) P22392, (Rat) P19804, (Mouse) Q01768
Entrez Gene ID: (Human) 4831, (Rat) 83782, (Mouse) 18103
DNA binding
transcription factor activity, sequence-specific DNA binding
nucleoside diphosphate kinase activity
protein histidine kinase activity
protein binding
ATP binding
metal ion binding
protein serine/threonine kinase activity
fatty acid binding
drug binding
intermediate filament binding
enzyme binding
nucleotide binding
kinase activity
transferase activity
kinase
purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell adhesion
integrin-mediated signaling pathway
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
peptidyl-histidine phosphorylation
negative regulation of apoptotic process
positive regulation of keratinocyte differentiation
regulation of epidermis development
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
mitophagy in response to mitochondrial depolarization
negative regulation of myeloid leukocyte differentiation
positive regulation of neuron projection development
positive regulation of cAMP biosynthetic process
cellular response to oxidative stress
regulation of apoptotic process
protein autophosphorylation
protein oligomerization
response to growth hormone
cellular response to glucose stimulus
cellular response to fatty acid
nucleotide metabolic process
phosphorylation
