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Invitrogen
NME5 Monoclonal Antibody (4F5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-20379
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4F5
抗原
NME5 (NP_003542, 121 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2-1.0 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: DLRNALHGSN DFAAAEREIR FMFPEVIVEP IPIGQAAKDY LNLHIMPTLL EGLTELCKQK PADPLIWLAD WLLKNNPNKP KLCHHPIVEE PY
靶标信息
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exonuclease NME5; inhibitor of p53-induced apoptosis-beta; IPIA-beta; NDK-H 5; NDP kinase homolog 5; non-metastatic cells 5 protein expressed in; non-metastatic cells 5 protein expressed in (nucleoside-diphosphate kinase) isoform NME5_1; non-metastatic cells 5 protein expressed in (nucleoside-diphosphate kinase) isoform NME5_3; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); putative 3'-5'-DNA exonuclease NDK5; radial spoke 23 homolog; radial spoke head protein 23 homolog; testis-specific nm23 homolog; unnamed protein product
基因别名: CILD48; NDK5; NM23-H5; NM23H5; RSPH23
UniProt ID: (Human) P56597
Entrez Gene ID: (Human) 8382
cilium movement
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
DNA catabolic process
spermatogenesis
spermatid development
nucleoside metabolic process
sperm motility
spermatid differentiation
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
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