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Abnova
NMNAT2 Monoclonal Antibody (2G8)
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产品信息
H00023057-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G8
抗原
NMNAT2 (AAH20998, 1 a.a. approximately 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: MEIQELEEIQ ACQGLWEVFV TLSERARDYL HKTGRFIVIG GIVSPVHDSY GKQGLVSSRH RLIMCQLAVQ NSDWIRVDPW ECYQDTWQTT CSVLEHHRDL MKRVTGCILS NVNTPSMTPV IGQPQNETPQ PIYQNSNVAT KPTAAKILGK VGESLSRICC VRPPVERFTF VDENANLGTV MRYEEIELRI LLLCGSDLLE SFCIPGLWNE ADMEVIVGDF GIVVVPRDAA DTDRIMNHSS ILRKYKNNIM VVKDDINHPM SVVSSTKSRL ALQHGDGHVV DYLSQPVIDY ILKSQLYINA SG
靶标信息
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NaMN adenylyltransferase 2; Nicotinamide mononucleotide adenylyltransferase 2; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinate-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMN/NaMN adenylyltransferase 2; pyridine nucleotide adenylyltransferase 2
基因别名: C1orf15; KIAA0479; NMNAT2; PNAT2
UniProt ID: (Human) Q9BZQ4
Entrez Gene ID: (Human) 23057
