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Invitrogen
NOX5 Polyclonal Antibody
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产品信息
PA5-79753
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human NOX5 (747-765aa KVLKGHCEKFGFRFFQENF).
偶联物
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: 22RV1 whole cell, PANC whole cell, HELA whole cell, SKOV whole cell. IHC: Human Mammary Cancer Tissue. ICC/IF: HELA Cell.
靶标信息
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NADPH oxidase 5; NADPH oxidase, EF-hand calcium binding domain 5; NOX5 alpha; NOX5 gamma; NOX5S; NOX5zeta; unnamed protein product
基因别名: NOX5
UniProt ID: (Human) Q96PH1
Entrez Gene ID: (Human) 79400
calcium ion binding
protein binding
hydrogen ion channel activity
superoxide-generating NADPH oxidase activity
oxidoreductase activity
heme binding
metal ion binding
flavin adenine dinucleotide binding
NADP binding
oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
superoxide-generating NADPH oxidase activity
angiogenesis
positive regulation of cytokine production
endothelial cell proliferation
ion transport
apoptotic process
defense response
ion transmembrane transport
superoxide anion generation
regulation of fusion of sperm to egg plasma membrane
cytoskeleton-dependent cytokinesis
hydrogen ion transmembrane transport
positive regulation of reactive oxygen species metabolic process
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