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Invitrogen
NPAT Polyclonal Antibody
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产品信息
PA5-65419
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VNQAVSPNFSQ GSAIIIASPV QPVLQGMVGM IPVSVVGQNG NNFSTPPRQV LHMPLTAPVC NRSIPQFPVP PKSQKAQGLR NKPCIGKQVN NLVDSSGHSV
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 85%.
靶标信息
Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nuclear protein of the ataxia telangiectasia mutated locus; Nuclear protein of the ATM locus; nuclear protein, ataxia-telangiectasia locus; nuclear protein, co-activator of histone transcription; p220; Protein NPAT
基因别名: CAND3; E14; E14/NPAT; NPAT; p220
UniProt ID: (Human) Q14207
Entrez Gene ID: (Human) 4863
