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7TM Antibodies
NPB, Neuropeptide B Polyclonal Antibody
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NPB, Neuropeptide B Antibody (7TM0NPB-IC) in IHC (P)
Immunohistochemical identification of Neuropeptide B (NPB) in rat hypothalamus. Rats were treated with an intracerebroventricular injection with 100 µg col chi cine (10 µg/mu l) followed by vascular perfusion and fixation. Sections were dewaxed, microwaved in citric acid, and incubated with anti-NPB (Neuropeptide B) antibody (7TMNPB-IC) at a dilution of 1:100 or incubated with the same antibody in the same ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
7TM0NPB-IC
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide presents amino acids 1-20 of human NPB.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
Dulbecco's PBS, pH 7.4
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Neuropeptide B is a endrogenous ligand of the orphan G protein coupled receptor GPR7. NPB and GPR7 exist in close proximity in the rat hypothalamus, and are ideally positioned to modulate neuroendocrine functions. NPB-immunoreactivity was enriched in many regions within the hypothalamus which also contained high levels of GPR7 mRNA including the ventrormedial hypothalamic nucleus, dorsomedial hypothalamic nucleus, arcuate nucleus, supraoptic retrochiasmatic nucleus, and in the area ventral to the zona incerta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ligand of the GPR7 receptor; prepro-NPB; preproneuropeptide B; preproprotein L7; rPPL7; unnamed protein product
基因别名: L7; mPPL7; PPL7; PPNPB
UniProt ID: (Human) Q8NG41, (Mouse) Q8K4P1, (Rat) Q8K4P2
Entrez Gene ID: (Human) 256933, (Mouse) 208990, (Rat) 259222
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
feeding behavior
protein ubiquitination
anaphase-promoting complex-dependent catabolic process
positive regulation of mitotic metaphase/anaphase transition
protein K48-linked ubiquitination
protein K11-linked ubiquitination
protein branched polyubiquitination
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