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Alomone Labs, LTD
NPY2R Polyclonal Antibody
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NPY2R Antibody (ANR-022-200UL) in ICC/IF
Expression of neuropeptide Y2receptor in rat dorsal root ganglion cells - Immunocytochemical staining of rat dorsal root ganglion (DRG) neurons. A, D. A paraformaldehyde-fixed and permeabilized DRG primary culture was stained with Anti-NPY2R Antibody (#ANR-022), (1:100) followed by Alexa-555-conjugated goat Anti-rabbit secondary Antibody . B, E. Nuclear fluorescence staining of cells using the membrane-permeable DNA dye Hoechst 33342. C. Merged images of panels A and B. F. Merged images of panels D and E. Magnification:A-C: x20E-F: x100.
产品信息
ANR-022-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CEQRLDAIHSEVSMTFKAK, corresponding to amino acid residues 346-364 of mouse NPY2R, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC124241; MGC124242; MGC124244; Neuropeptide Y receptor type 2; neuropeptide Y receptor Y2-like; Neuropeptide y-y2; neuropeptide Y-Y2 receptor; neuropeptide Y/peptide YY-Y2 receptor; NPY-Y2 receptor; NPY2-R; Y2 receptor
基因别名: NPY2-R; Npy2r
UniProt ID: (Mouse) P97295
Entrez Gene ID: (Mouse) 18167, (Rat) 66024
behavioral fear response
positive regulation of peptide secretion
outflow tract morphogenesis
cardiac left ventricle morphogenesis
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
nitric oxide mediated signal transduction
chemical synaptic transmission
positive regulation of cell-substrate adhesion
negative regulation of cAMP biosynthetic process
negative regulation of neurological system process
positive regulation of dopamine secretion
positive regulation of smooth muscle contraction
positive regulation of circadian sleep/wake cycle, non-REM sleep
secretion
negative regulation of synaptic transmission
negative regulation of secretion
regulation of sensory perception of pain
negative regulation of synaptic transmission, glutamatergic
negative regulation of excitatory postsynaptic potential
negative regulation of feeding behavior
positive regulation of cell adhesion
