Search
Abnova
NR1D1 Monoclonal Antibody (3G5)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00009572-M17
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3G5
抗原
NR1D1 (NP_068370, 233 a.a. approximately 322 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: SQCPLETSPT QHPTPGPMGP SPPPAPVPSP LVGFSQFPQQ LTPPRSPSPE PTVEDVISQV ARAHREIFTY AHDKLGSSPG NFNANHASG
靶标信息
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: BD73; EAR-1R; nuclear receptor Rev-ErbA-alpha; Rev-erba; rev-erbA-alpha; Rev-ErbAalpha; Reverbaalpha; RVR; unnamed protein product; V-erbA-related protein 1
基因别名: ear-1; EAR1; hRev; REVERBA; REVERBalpha; THRA1; THRAL
UniProt ID: (Human) P20393
Entrez Gene ID: (Human) 9572
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription corepressor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
heme binding
sequence-specific DNA binding
E-box binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
cellular glucose homeostasis
glycogen biosynthetic process
regulation of transcription, DNA-templated
hormone-mediated signaling pathway
proteasomal protein catabolic process
regulation of lipid metabolic process
cell differentiation
intracellular steroid hormone receptor signaling pathway
intracellular receptor signaling pathway
protein destabilization
circadian regulation of gene expression
negative regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
regulation of circadian sleep/wake cycle
regulation of circadian rhythm
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to leptin
regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
circadian temperature homeostasis
regulation of insulin secretion involved in cellular response to glucose stimulus
regulation of type B pancreatic cell proliferation
negative regulation of astrocyte activation
positive regulation of bile acid biosynthetic process
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
negative regulation of cold-induced thermogenesis
negative regulation of neuroinflammatory response
negative regulation of microglial cell activation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
