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Invitrogen
NR1D2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100648
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NR1D2(Accession Q14995), corresponding to amino acid residues M447-Q497.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total NR1D2.
靶标信息
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EAR-1R; EAR4; HZF2; Nuclear receptor subfamily 1 group D member 2; Orphan nuclear hormone receptor BD73; orphan nuclear receptor HZF-2; Orphan nuclear receptor RVR; orphan receptor; Rev-erb alpha-related receptor; Rev-erb beta; Rev-erb-beta; Rev-erb-Beta2; Rev-erba beta; Rev-ErbA-beta; Rev-erbabeta; RVR; V-erbA-related protein 1-related
基因别名: HZF-2; NR1D2; Rev-erb; RVR
UniProt ID: (Mouse) Q60674, (Rat) Q63504
Entrez Gene ID: (Mouse) 353187, (Rat) 259241
core promoter sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
thyroid hormone receptor activity
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of lipid metabolic process
regulation of circadian rhythm
steroid hormone mediated signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of inflammatory response
lipid homeostasis
regulation of energy homeostasis
regulation of skeletal muscle cell differentiation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
