Search
Invitrogen
NR2C2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
NR2C2 Antibody (PA5-117047) in WB
Western blot analysis of NR2C2 in 293F cells. Samples were incubated with NR2C2 Polyclonal antibody (Product # PA5-117047) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-117047
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NR2C2 (NP_0032892)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.96 mg/mL
规格
196 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: MCF7, HeLa, Jurkat, 293T, Mouse brain, Mouse spleen, Mouse thymus, Rat brain, Rat testis
Immunogen sequence: LIATPTFVAD KDGARQTGLL DPGMLVNIQQ PLIREDGTVL LATDSKAETS QGALGTLANV VTSLANLSES LNNGDTSEIQ PEDQSASEIT RAFDTLAKAL NTTDSSSSPS LADGIDTSGG GSIHVISRDQ STPIIEVEGP L
靶标信息
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Nuclear hormone receptor TR4; nuclear receptor subfamily 2, group H, member 2; orphan nuclear receptor TAK1; orphan nuclear receptor TR4; orphan receptor TR4; orphan receptor, TR4; testicular nuclear receptor 4; testicular receptor 4; TR2R1; TR4 orphan receptor; TR4-NS orphan receptor; type II zinc finger DNA binding transcription factor; unnamed protein product
基因别名: mKIAA4145; TAK1; TR4
UniProt ID: (Human) P49116, (Mouse) P49117, (Rat) P55094
Entrez Gene ID: (Human) 7182, (Mouse) 22026, (Rat) 50659
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
nervous system development
cell differentiation
intracellular receptor signaling pathway
tumor necrosis factor-mediated signaling pathway
positive regulation of embryonic development
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
spermatogenesis
cerebellum development
lipopolysaccharide-mediated signaling pathway
p38MAPK cascade
positive regulation of myoblast differentiation
positive regulation of behavior
meiotic cell cycle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
