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Invitrogen
NR2F1 Recombinant Rabbit Monoclonal Antibody (24GB430)
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NR2F1 Antibody (MA5-57133) in ICC/IF
Immunocytochemical staining of NR2F1 in HeLa cells using NR2F1 Recombinant Monoclonal Antibody (Product # MA5-57133) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; NR2F1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-57133
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB430
抗原
A synthesized peptide derived from human COUP TF1 (aa 1-53)
偶联物
形式
Liquid
浓度
0.65 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 3; chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; Nuclear receptor subfamily 2 group F member 1; nuclear receptor subfamily 2, group F, member 1; transcription factor COUP 1 (chicken ovalbumin upstream promoter 1, v-erb-a homolog-like 3); V-erbA-related protein 3
基因别名: BBOAS; BBSOAS; COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3; ERBAL3; NR2F1; NR2F2; SVP44; TCFCOUP1; TFCOUP1
UniProt ID: (Human) P10589, (Mouse) Q60632
Entrez Gene ID: (Human) 7025, (Rat) 81808, (Mouse) 13865
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription coactivator activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
retinoic acid-responsive element binding
DNA binding
metal ion binding
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
neuron migration
transcription, DNA-templated
nervous system development
positive regulation of receptor biosynthetic process
negative regulation of neuron projection development
cerebral cortex regionalization
forebrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
