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Invitrogen
NRK Polyclonal Antibody
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NRK Antibody (PA5-100912) in ICC/IF
Immunocytochemistry analysis of NRK in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with NRK polyclonal antibody (Product # PA5-100912) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-100912
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NRK(Accession Q7Z2Y5), corresponding to amino acid residues K292-I342.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total NRK.
靶标信息
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nck-interacting kinase-like embryo specific kinase; NESK; NIK-like embryo-specific kinase; Nik-related protein kinase
基因别名: AA407323; AA409510; AI225895; AV168563; AW538185; NESK; NRK
UniProt ID: (Human) Q7Z2Y5, (Mouse) Q9R0G8
Entrez Gene ID: (Human) 203447, (Mouse) 27206
receptor signaling protein serine/threonine kinase activity
ATP binding
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
activation of JNKK activity
parturition
negative regulation of cell proliferation
regulation of spongiotrophoblast cell proliferation
MAPK cascade
protein phosphorylation
regulation of mitotic cell cycle
phosphorylation
stress-activated protein kinase signaling cascade
actin cytoskeleton reorganization
regulation of apoptotic process
neuron projection morphogenesis
