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Invitrogen
NTE Polyclonal Antibody
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产品信息
PA5-52446
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DVGYQYGKAV FGGWSRGNVI EKMLTDRRST DLNESRRADV LAFPSSGFTD LAEIVSRIEP PTSYVSDGCA DGEESDCLTE YEEDAGPDCS RDEGGSPEGA SPSTASEMEE EKSILRQRR
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
靶标信息
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD73; Neuropathy target esterase; patatin-like phospholipase domain containing 6; Patatin-like phospholipase domain-containing protein 6
基因别名: BNHS; iPLA2delta; LNMS; NTE; NTEMND; OMCS; PNPLA6; SPG39; sws
UniProt ID: (Human) Q8IY17
Entrez Gene ID: (Human) 10908
