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Invitrogen
NTF4 Polyclonal Antibody, PeproTech®
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NTF4 Antibody (500-P83-1MG) in ELISA
Sandwich ELISA: To detect Human NT-4 by sandwich ELISA (using 100 µl/well) a concentration of 0.5-2.0 µg/mL of NT4 Polyclonal Antibody (Product # 500-P83-1MG) is required. This antigen affinity purified antibody, in conjunction with PeproTech NT4 Polyclonal Antibody, Biotin (Product # 500-P83BT-500UG) as a detection antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human NT-4.
产品信息
500-P83-1MG
产品规格
种属反应
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived, 28.1kDa Recombinant Human NT-4
偶联物
形式
Lyophilized
纯化类型
Affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
AA Sequence of recombinant protein (monomer): GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human NT-4. Anti-Human NT-4-specific antibody was purified by affinity chromatography employing an immobilized Human NT-4 matrix.
Sandwich ELISA: To detect Human NT-4 by sandwich ELISA (using 100 µL/well) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human NT-4 (500-P83BT) as a detection antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human NT-4.
Western Blot: To detect Human NT-4 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Human NT-4 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
靶标信息
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neurotrophic factor 4; neurotrophic factor 5; Neurotrophin 4/5; neurotrophin 5 (neurotrophin 4/5); Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; Neutrophic factor 5; NT-4; NT-5; NT4/NT5
基因别名: GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT5; NTF4; NTF5
UniProt ID: (Human) P34130
Entrez Gene ID: (Human) 4909
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
ganglion mother cell fate determination
long-term memory
sensory organ boundary specification
adult locomotory behavior
epidermis development
mechanoreceptor differentiation
negative regulation of neuron apoptotic process
regulation of neuron differentiation
neuron projection morphogenesis
innervation
taste bud development
