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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SYYPRKYDAK FTDFSLPPSR KQKKKKRKEP VFHFFCDTCD RGFKNQEKYD KHMSEHTKCP ELDCSFTAHE KIVQFHWRNM
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FMR1-interacting protein NUFIP1; Nuclear FMR1-interacting protein 1; Nuclear FMRP-interacting protein 1
基因别名: NUFIP1
Entrez Gene ID: (Human) 26747