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Invitrogen
NUP50 Polyclonal Antibody
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NUP50 Antibody (PA5-97215) in IHC (P)
Immunohistochemistry analysis of NUP50 in paraffin-embedded rat testis. Samples were incubated with NUP50 Polyclonal antibody (Product # PA5-97215) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
PA5-97215
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 340-468 of human NUP50 (NP_0091032)
偶联物
形式
Liquid
浓度
1.67 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ENDEPPKVVV TEVKEEDAFY SKKCKLFYKK DNEFKEKGIG TLHLKPTANQ KTQLLVRADT NLGNILLNVL IPPNMPCTRT GKNNVLIVCV PNPPIDEKNA TMPVTMLIRV KTSEDADELH KILLEKKDA
Positive Samples: HeLa, Jurkat, Mouse thymus; Cellular Location: Nucleoplasmic side, Nucleus, Nucleus membrane, Peripheral membrane protein, nuclear pore complex
靶标信息
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 50 kDa nucleoporin; CTA-268H5.7; DKFZP564A043; MGC39961; nuclear pore associated protein 60 kDa; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; NUP50 protein; OTTHUMP00000199530
基因别名: 1700030K07Rik; AI413123; NPAP60; NPAP60L; NUP50; PRO1146; Rtp60
UniProt ID: (Human) Q9UKX7, (Rat) O08587, (Mouse) Q9JIH2
Entrez Gene ID: (Human) 10762, (Rat) 25497, (Mouse) 18141
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
intracellular transport of virus
regulation of cellular response to heat
neural tube formation
protein transport
intracellular transport
mRNA transport
nucleocytoplasmic transport
