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Invitrogen
NUS1 Polyclonal Antibody
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产品信息
PA5-70767
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse NUS1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 93%
靶标信息
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dehydrodolichyl diphosphate syntase complex subunit Nus1; Dehydrodolichyl diphosphate synthase complex subunit Nus1; di-trans,poly-cis-decaprenylcistransferase; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog
基因别名: 1600027K07Rik; AU019165; AW538011; BC003223; D10Ertd438e; Ngbr; Nus1
UniProt ID: (Mouse) Q99LJ8
Entrez Gene ID: (Mouse) 52014
