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Invitrogen
Naja kaouthia Cobra Venom Factor Polyclonal Antibody
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Naja kaouthia Cobra Venom Factor Antibody (PA5-117705) in WB
Western Blot analysis of Cobra Venom Factor using Naja kaouthia Cobra Venom Factor Polyclonal Antibody (Product # PA5-117705) at 3 µg/mL. Positive WB detected in Recombinant protein. Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa
产品信息
PA5-117705
产品规格
种属反应
Reptile
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Naja kaouthia Cobra venom factor protein (733-984aa)
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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