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Invitrogen
Natamycin Recombinant Mouse Monoclonal Antibody (3E5)
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Natamycin Antibody (MA566404) in SDS-PAGE
SDS-PAGE characterization of Natamycin under reducing conditions. Lane M: Protein marker (kDa); Lane NTM: Purified Natamycin Recombinant Monoclonal (Product # MA566404). Natamycin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-418.
产品信息
MA566404
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3E5
抗原
Conjugate of NTM hapten and KLH.
偶联物
形式
Liquid
浓度
5.2 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Natamycin is a polyene macrolide antibiotic with strong antifungal properties, produced by Streptomyces natalensis. It functions by binding to ergosterol in fungal cell membranes, disrupting membrane integrity and inhibiting fungal growth and reproduction. Natamycin is commonly used as an antifungal food preservative due to its ability to prevent mycotoxin formation. Structurally, it is characterized by a large macrolide ring and conjugated double bonds, which contribute to its antifungal activity. Gene engineering has enabled the creation of natamycin analogs with enhanced properties, by modifying post-polyketide synthase tailoring enzyme encoding genes. This antibiotic is also used in medical applications, such as treating fungal keratitis, where its formulation challenges are addressed by developing natamycin-loaded nanomicelles to improve corneal permeability and reduce irritation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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