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Invitrogen
Neurogenin 1 Monoclonal Antibody (OTI3F9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-24900
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI3F9
抗原
Full length human recombinant protein of NEUROG1 produced in HEK293T cell
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
规格
100 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: class A basic helix-loop-helix protein 6; neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; neurogenic differentiation factor 3; NGN-1; unnamed protein product
基因别名: AKA; bHLHa6; CCDDRD; Math4C; NEUROD3; ngn1
UniProt ID: (Human) Q92886
Entrez Gene ID: (Human) 4762
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein homodimerization activity
protein dimerization activity
E-box binding
sequence-specific double-stranded DNA binding
regulation of transcription from RNA polymerase II promoter
thorax and anterior abdomen determination
nervous system development
sensory organ development
trigeminal nerve development
vestibulocochlear nerve formation
peristalsis
forebrain development
auditory behavior
genitalia morphogenesis
inner ear morphogenesis
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
regulation of muscle organ development
genitalia development
inner ear development
neuromuscular process controlling balance
axon development
mastication
cochlea development
cochlea morphogenesis
craniofacial suture morphogenesis
learned vocalization behavior
negative regulation of relaxation of muscle
negative regulation of saliva secretion
hard palate morphogenesis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
