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Invitrogen
Neuroligin 1 Polyclonal Antibody
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Neuroligin 1 Antibody (PA5-48050) in IHC (F)
Immunohistochemical analysis of Neuroligin 1 in perfusion fixed frozen sections of rat brain (cortex). Samples were incubated in Neuroligin 1 polyclonal antibody (Product # PA5-48050) using a dilution of 10 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to neuronal cell bodies, pr... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-48050
产品规格
种属反应
Human,
Rat
已发表种属
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant rat Neuroligin1/NLGN1 Gln46-Leu696
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects recombinant rat Neuroligin 1/NLGN1 in direct ELISAs.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC45115; Neuroligin I; Neuroligin-1; NLG 1
基因别名: KIAA1070; NLGN1
UniProt ID: (Rat) Q62765
Entrez Gene ID: (Rat) 116647
regulation of respiratory gaseous exchange by neurological system process
protein targeting
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
nervous system development
synapse assembly
metabolic process
positive regulation of circadian sleep/wake cycle, wakefulness
synaptic vesicle targeting
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of synaptic transmission, GABAergic
protein localization to synapse
neuronal ion channel clustering
establishment of protein localization
regulation of neuron differentiation
rhythmic process
cytoskeletal matrix organization at active zone
modulation of synaptic transmission
synapse organization
protein homooligomerization
protein heterotetramerization
positive regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
inhibitory postsynaptic potential
positive regulation of dendritic spine development
terminal button organization
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
neurexin clustering involved in presynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
positive regulation of ruffle assembly
positive regulation of synaptic vesicle endocytosis
positive regulation of intracellular signal transduction
positive regulation of synaptic vesicle exocytosis
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
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