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Invitrogen
Neurophysin II Polyclonal Antibody
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产品信息
PA5-148460
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Neurophysin II, Cys20-Tyr164
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Neurophysin II is a carrier protein encoded by the AVP gene located on chromosome 20 in humans. It plays a crucial role in the transport and storage of the hormone vasopressin, also known as antidiuretic hormone (ADH). Vasopressin is essential for regulating water balance in the body by promoting water reabsorption in the kidneys. Neurophysin II binds to vasopressin in the neurosecretory vesicles of the hypothalamus and facilitates its transport to the posterior pituitary gland, where vasopressin is stored and later released into the bloodstream. Mutations in the AVP gene can result in conditions such as familial neurohypophyseal diabetes insipidus, characterized by an inability to concentrate urine and maintain proper water balance. Neurophysin II, therefore, is integral to maintaining homeostasis through its role in the vasopressin pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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