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Immunogen sequence: GLIADSQISA SSTQEYLWSP SAARLVSSRS GWFPRIPQAQ PGEEWLQVDL GTPKTVKGVI IQGARGGDSI TAVEARAFVR KFKVSYSLNG KDWEYIQDPR TQQPKLFEGN MHYDTPDIRR FDPIPAQYVR VYPERWSPAG IGMRLEVLGC DWTDSKPTVE TLGPTVKSEE TTTPYPTEEE ATECGENCSF EDDKDLQLPS GFNCNFDFLE EPCGWMYDHA KWLRTTWASS SSPNDRTFPD DRNFLRLQSD SQREGQYARL ISPPVHLPRS PVCMEFQYQA TGGRGVALQV VREASQES; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Membrane, Single-pass type I membrane protein
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2
基因别名: 1110048P06Rik; Np-2; Np2; Npn-2; Npn2; Nrp2
UniProt ID: (Mouse) O35375, (Rat) O35276
Entrez Gene ID: (Mouse) 18187, (Rat) 81527
分子生物学功能: oxidoreductase